Case Studies & Papers
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Journal
| Title |
Polyhexamethylene Biguanide (PHMB): An Addendum to Current Topical Antimicrobials |
Download File |
| Author |
Mulder, GD Cavorsi, JP Lee, DK |
| Publication |
Wounds 2007;19(7):173-182 |
| Key Points |
Literature review advised that more evidence for silver efficacy is required and examined the effectiveness of gauze-based PHMB products. PHMB does not have a history of cytotoxicity. |
| Title |
PHMB action in a new wound dressing |
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| Author |
Kingsley et al |
| Publication |
Wounds UK Journal, 2009:Vol.5:No.7 |
| Key Points |
There is currently a rising prevalence of MRSA and much criticism around the indiscriminate use of antibiotics, and evidence of bacterial resistance to some antiseptics such as silver. Topical antimicrobials are probably the best way to reduce levels of bioburden in critically colonised wounds to facilitate wound healing. |
| Title |
PHMB to prevent wound infection |
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| Author |
Moore and Gray |
| Publication |
Wounds UK Journal, 2007:Vol.5,No.2 |
| Key Points |
Article reviews the evidence for efficacy and cost-effectiveness of anti-microbial dressings in the prevention of surgical site infections, when routinely used in standard wound care protocols. Multiple clinical papers reviewed. Definition and explanation given of the Infection Continuum. |
| Title |
PHMB the clinical evidence |
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| Author |
Deborah Glover and Gill Wicks |
| Publication |
Journal of Wound Care Supplement - November 2009 |
| Key Points |
Paper discussing the clinical evidence and the effectiveness of Suprasorb X+PHMB in reducing pain and infection. Paper gives concise literature reviews on clinical evidence and pain. 4 week evaluation on 15 patients using Suprasorb X+PHMB including non-healing wounds, history of recurrent infections, wounds with devitalised tissue requiring debridement. |
| Title |
PHMB: a well tolerated antiseptic with no reported toxic effects |
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| Author |
S Gilliver |
| Publication |
Journal of Wound Care Supplement - November 2009 |
| Key Points |
Aim to review the in vitro and in vivo evidence of Suprasorb X+PHMB on its safety, tolerability and efficacy. Also looks at cost savings in clinical practice. |
| Title |
Role of topical antimicrobials |
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| Author |
Georgina Gethin |
| Publication |
Journal of Wound Care Supplement - November 2009 |
| Key Points |
Gives explanation of the bioburden continuum and the role of bacteria in wounds within it. Gives recommendations on the best use of antimicrobials and describes the difference between antibiotics and antiseptics. |
| Title |
Bacterial Management in Modern Wound Care |
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| Author |
Martyn Butcher |
| Publication |
Wound Essentials, Volume 5, 2010;119-126 |
| Key Points |
Successful management of bacteria in the wound is a complex issue. The role of bacterial management is therefore of great importance, particularly for those with a compromised immune response. |
| Title |
Managing the 'at risk' patient: minimizing the risk of wound infection |
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| Author |
Trudie Young, Andrew Kingsley, Claire Acton |
| Publication |
British Journal of Nursing Supplement - November 2010 |
| Key Points |
Looking at patients deemed at risk of infection |
| Title |
A clinical audit of Suprasorb X+PHMB |
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| Author |
S Fumarola, M Butcher, P Cooper, D Gray, F Russell, S Stringfellow, M Bertram, K Duguid, G Pirie, |
| Publication |
Wounds UK Journal 2010, Vol.6, No.3 |
| Key Points |
Looking at efficacy of SuprasorbX+PHMB |
| Title |
Clinical evaluation of a PHMB impregnated biocellulose dressing on paediatric lacerations |
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| Author |
J.G. Alblas,1 PA, A. Andriessen,2 PA , PhD et al. |
| Publication |
Journal of wound care vol 2 0 , no 6 , june 2 0 1 1 |
| Key Points |
SuprasorbX+PHMB was used on 20 Dutch children with painful heel injuries from being caught in bicycle spokes. |
| Title |
A cohort study on the efficacy of a polyhexanide-containing biocellulose dressing in the treatment of biofilms in wounds |
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| Author |
E. Lenselink, RN, MA, A. Andriessen, PA , PhD |
| Publication |
Journal of wound care vol 2 0 , no 1 1 , Novemb er 2 0 1 1 |
| Key Points |
The results suggest that continuous application of SuprasorbX+PHMB reduced biofilm in the stagnating wounds in the study. |
| Title |
Comparison of PHMB-containing dressing and silver dressings in patients with critically colonised or locally infected wounds |
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| Author |
T. Eberlein et al. |
| Publication |
Journal of wound care vol 2 1 , no 1 , January 2 0 1 2 |
| Key Points |
Both SuprasorbX+PHMB were effective in reducing pain and bacterial burden. However, SuprasorbX+PHMB was significantly faster and better in removing the critical bacterial load. |
| Title |
PHMB: an effective antimicrobial in wound bioburden management |
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| Author |
Martyn Butcher |
| Publication |
British Journal of Nursing, Vol 21, No 12 |
| Key Points |
PHMB seems to meet the criteria for an ideal dressing as described by Drosou et al (2003) |
| Title |
Demystifying the complexities of wound healing |
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| Author |
Andrew Sharpe,Michael Concannon |
| Publication |
Wounds UK 2012 vol:12 |
| Key Points |
Article by 2 specialist podiatrists on treating problem foot wounds. including "at risk" and infected wounds. |
| Title |
SuprasorbX+PHMB made easy |
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| Author |
Kingsley A, Kiernan M |
| Publication |
Wounds UK |
| Key Points |
Discussing the role of SuprasorbX+PHMB, focusing on pain reduction in infected wounds. |
| Title |
Examining the multifactorial nature of wound infection |
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| Author |
June Jones |
| Publication |
Wound Essentials 2012 |
| Key Points |
The article discusses the difficulties of diagnosing wound infection |
| Title |
Understanding Wound Infection Skills for Practice |
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| Author |
John Timmons et al |
| Publication |
Wounds UK 2009 |
| Key Points |
A booklet of case studies and papers where Suprasorb+PHMB has been used |
