Case Studies & Papers
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Case study
| Title |
Multi-treatment approach to complex wound management of a circumferential leg wound caused by cellulitis |
Download File |
| Author |
Jane Barker Community Matron, Leg Ulcer Specialist |
| Publication |
Poster Presentation: EWMA Conference, Helsinki - May 2009 |
| Key Points |
Case study Case study of Leukaemia patient with extensive tissue loss due to episode of cellulitis. Patient had a lowered immune system, VAS pain score 10/10. |
| Title |
Use of superabsorbent and antimicrobial dressings under compression |
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| Author |
Agnes Collarte & Zoe Lear St Charles Hospital, TV Department |
| Publication |
Poster Presentation, Wounds UK Conference, Harrogate - November 2010 |
| Key Points |
All three patients had severe pain and were suffering from maceration damage from high levels of exudate.Pain reduction and healing was achieved. |
| Title |
Multi-treatment approach to complex wound management of a circumferential leg wound caused by cellulitis |
Download File |
| Author |
Jane Barker Leg Ulcer Specialist |
| Publication |
Poster Presentation: EWMA Conference, Helsinki - May 2009 |
| Key Points |
Leukaemia patient with extensive tissue from cellulitis. Patient had a lowered immune system. |
| Title |
HydroBalanced wound dressing and a ready-to-wear compression device in the treatment of venous leg ulcers |
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| Author |
Mosti, Mataliano Spengler Abel |
| Publication |
Poster Presentation, Wounds UK Harrogate, November 2008 |
| Key Points |
13 leg ulcer patient clinical study |
| Title |
New HydroBalanced wound concept study in primary sector |
Download File |
| Author |
Nygaard R, Jorgensen SF - Denmark |
| Publication |
EWMA Conference, Lisbon, May 2008 |
| Key Points |
40 patient Clinical Study - Suprasorb X and Suprasorb X + PHMB (15 Case Studies) |
| Title |
Improvement of treatment of patients with venous leg ulcers by a new pain-reducing wound dressing with HydroBalance |
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| Author |
Dini, Bertone, Barbanera, Brill, Romanelli - Italy |
| Publication |
Poster Presentation, Wounds UK Harrogate, November 2008 |
| Key Points |
25 patient Clinical Study comparing Suprasorb X and Suprasorb P (foam dressing) with Suprasorb P (foam) alone. Single-blinded, mono-centric, prospective, controlled, randomised explorative comparison measured the trans--epidermal water loss (TEWL), redness for inflammation, skin hydration, wound size and pain. |
| Title |
Biocompatibility study on a HydroBalanced wound dressing |
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| Author |
Wiegand, Abel, Kramer, Muller, Ruth, Hipler - Germany |
| Publication |
Poster Presentation, EWMA Conference, Lisbon - May 2008 |
| Key Points |
Laboratory measurement of ATP content (Adenosine Triphosphate) donor of energy to cells. |
| Title |
A comparative study investigating the autolytic wound dressing potential of the Suprasorb X moist cellulose dressing and the Aquacel dry cellulose dressing in chronic venous leg ulcers with fibrinous coating |
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| Author |
Wild Th, Eberlein Th - Austria and Germany |
| Publication |
Wounds UK, Harrogate, November 2008 |
| Key Points |
Suprasorb X v Aquacel - Unpublished study - 10 patient randomised, prospective, controlled, exploratative (RCT) Comparison with Aquacel, with compression, wound cleansing (debridement), moisture absorption and donation, skin improvement, comfort, pain. Autolytic wound cleansing potential of different cellulose-based dressings. |
| Title |
Efficacy of different wound dressings on artificial plaques of fibrin |
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| Author |
Korber, Seipp, Hofmann - Germany (Laboratory) |
| Publication |
Poster Presentation, EWMA Conference, Lisbon - May 2008 |
| Key Points |
Biofilms, Fibrin Plaques. Comparison with foam, alginate, alginate with silver. Lowest fibrin reduction was shown in foam, PHMB dressing significantly better at fibrin- rest reduction b) Biofilm fibrin resistances – antibacterial measures with focus on polihexamide. |
| Title |
Prospective evaluation of Suprasorb X in chronic wounds. |
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| Author |
Coerper S, Beckerts, Halm-Nill C, Deutschle-G, Konigsrainer A - Germany |
| Publication |
Poster Presentation, EWMA Conference, Prague - May 2008 |
| Key Points |
96 patient (134 ulcers) Clinical study with Suprasorb X - hard to heal leg ulcers (healing), pain, safety. |
| Title |
Prospective, randomized, controlled, multi-center clinical study of a biocellulose wound dressing for the treatment of venous ulcer patients |
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| Author |
T Phillips, Department of Dermatology, Boston, USA A Andriessen, Consultant & UMC, Netherlands et al |
| Publication |
Poster presentation at Wounds UK, Harrogate - November 2010 |
| Key Points |
An American clinical study comparing the effectiveness of Suprasorb X with compression therapy with a non-adherent contact layer with compression in 46 ‘hard to heal’ venous ulcers in an outpatient setting. |
| Title |
New HydroBalanced wound concept study in primary sector |
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| Author |
Nygaard R, Jorgensen SF |
| Publication |
EWMA Conference, Lisbon, May 2008 |
| Key Points |
40 patient study with critically colonised/infected wounds. Looking at wound bed preparation, ease of use, bioburden and pain. |
| Title |
First Italian experience with a polyhexanide containing HydroBalanced wound dressing in hospitalised patients with critically colonised or infected chronic wounds. |
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| Author |
Mosti, Mattaliano, Schmitz, Abel |
| Publication |
Poster Presentation, Wounds UK Harrogate, November 2008 |
| Key Points |
18 patients (30 wounds) with critically-colonised/infected wounds. Parameters – wound bed preparation time, ease of use, bioburden, pain, side-effects. |
| Title |
Successful therapy of critically-colonised or locally-infected wounds with a new hydrobalanced biocellulose-based wound dressing with polyhexanide on outpatients |
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| Author |
Mosti, Mattaliano, Schmitz, Abel |
| Publication |
Poster Presentation, Wounds UK Harrogate, November 2008 |
| Key Points |
60 patients (11 with critically colonized or locally infected wounds), antimicrobial action, donation and absorption, use under compression ,ulcer healing, bacterial burden, pain, and periwound skin. |
| Title |
Efficacy of different wound dressings on artificial plaques of fibrin |
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| Author |
Korber, Seipp, Hofmann |
| Publication |
Poster Presentation, EWMA Conference, Lisbon - May 2008 |
| Key Points |
Biofilms, Fibrin plaques comparison with foam, alginate, alginate with silver. Lowest fibrin reduction was shown in foam, PHMB dressing significantly better at fibrin- rest reduction effect on organisms: Pseudomonas, Staphylococcus Aureus. |
| Title |
Protective effect of polyhexanide on HaCaT keratinocytes in co-culture with staphylococcus aureus. |
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| Author |
Wiengand, Abel, Ruth, Hipler |
| Publication |
Poster Presentation, Wounds UK Harrogate, November 2008 |
| Key Points |
Laboratory trial - showing effectiveness against MRSA and safety to healthy cells. |
| Title |
Approaches to therapy and an outlook on improving the clinical data situation, with a special focus on the polihexanide-containing Suprasorb X+PHMB HydroBalanced dressing. |
Download File |
| Author |
Eberkin T, Wild T |
| Publication |
Extended abstracts of presentations at EWMA Conference, Lisbon, 2008 - L&R Publication |
| Key Points |
Suprasorb X+PHMB - 1 unpublished Clinical case study - Wounds and MRSA treated for 5 days with daily dressing changes. Suprasorb X+PHMB followed by Suprasorb X for 3 days |
| Title |
Reducing Bacterial Loading & the Effect on Wound Healing with Suprasorb X+PHMB |
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| Author |
Sylvia Hampton |
| Publication |
Poster Presentation: EWMA Conference, Helsinki - May 2009 |
| Key Points |
Ongoing work investigating the reduction of pH and bacteria levels in wounds using Suprasorb X+PHMB. wound 0.5cm depth. Wound resistant to most previous antimicrobials. |
| Title |
Case study: The care of a patient with a large & chronic venous ulcer using a highly absorptive dressing and an antimicrobial dressing |
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| Author |
Martin Tadej and Anna Colbourne |
| Publication |
Activa Publication |
| Key Points |
Case study of a middle aged, obese, poorly mobile, employed lady with previously highly exuding ulcer. Exudate managed with Flivasorb. Following this regime, aim was to eliminate and control the proliferation of bacteria in the wound. The use of Suprasorb X+PHMB resulted in the removal of devitalised tissue. |
| Title |
Hydrobalanced cellulose based wound dressing with polyhexanide in surgical wounds (test with 20 patients) |
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| Author |
Anna Marie Nielsen |
| Publication |
Poster presentation at Wounds UK, Harrogate - November 2009 |
| Key Points |
20 patient study of Suprasorb X+PHMB applied to surgical wounds directly post operative and reviewing after 24 hrs. 80% of patients were diabetic. Operations included 11 amputations, 3 abscesses and 6 wounds with infection and osteomyelitis. |
| Title |
The management and treatment of an MRSA leg ulcer in a Raynaud’s patient |
Download File |
| Author |
Lynda Thomson |
| Publication |
Poster presentation at Wounds UK, Harrogate - November 2009 |
| Key Points |
59 year old lady with Raynauds disease and scleroderma pulmonary hypertension who sustained a friction wound to lateral gaiter aspect. Wound ulcerated, MRSA positive and pain score 4-6 VAS. Suprasorb X+PHMB applied under reduced compression. After 7 wks, routine MRSA swab returned negative. |
| Title |
Treatment of a skin flap laceration with Suprasorb X+PHMB |
Download File |
| Author |
Karen Hetherington |
| Publication |
Poster presentation at Wounds UK, Harrogate - November 2009 |
| Key Points |
Mixed aetiology traumatic leg ulcer 17cm x 20cm, large amounts of slough, clinical signs of infection including increased exudate, pain and erythema. Patient refused antibiotics. Suprasorb X+PHMB applied with a foam. After 3 days patient had no pain, visible signs of granulation and decreased redness. |
| Title |
The use of HCBD in the management of children with EB |
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| Author |
Jacqueline Denyer |
| Publication |
Poster presentation at Wounds UK, Harrogate - November 2009 |
| Key Points |
A study to discuss the use of Suprasorb X and Suprasorb X+PHMB in infants and children with EB. Criteria included those suffering from pain, itching and those with chronic wounds. 2 case studies discussed. |
| Title |
The use of Suprasorb X+PHMB on a recurring leg ulcer |
Download File |
| Author |
Fiona Kelly |
| Publication |
Poster presentation at Wounds UK, Harrogate - November 2009 |
| Key Points |
24 year old gentleman with a recurring ulcer wound following previous trauma. Patient previously suffered with cellulitis and osteomyelitis. Recurring wound was infected, malodorous, highly exuding, delay in healing and pain score 5/10 VAS. Suprasorb X+PHMB applied with a foam dressing. |
| Title |
The management of maceration in a Nursing Home environment |
Download File |
| Author |
Anna Paule |
| Publication |
Poster presentation at Wounds UK, Harrogate - November 2009 |
| Key Points |
72 year old paraplegic lady in a nursing home with 3 yr old grade 4 pressure ulcer with high levels of exudate. Wound initially dressed with Suprasorb A+Ag and Flivasorb three times a day. Suprasorb X+PHMB then used to pack wound and Flivasorb to cover. After 6 months patient no longer bed bound and goes out for lunch with friends. |
| Title |
No resistance after 100 days repeated incubation of staphylococcus aureus with polyhexanide |
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| Author |
Wiegand C¹, Abel M², Ruth P², Hipler C¹ - ¹Dept of Dermatology, Jena, Germany ²L&R, Rengsdorf, Germany |
| Publication |
Poster presentation at Wounds UK, Harrogate - November 2009 |
| Key Points |
No resistance after 100 days repeated incubation of staphylococcus aureus with polyhexanide .Antiseptics have a lower potency to induce bacterial resistance than antibiotics. Study carried out to measure the resistance capacity of Staphylococcus aureus to polyhexanide and silver nitrate. |
| Title |
Case study: 100 year old lady with leg wound |
Download File |
| Author |
Sian Fumarola |
| Publication |
EWMA Congress Brochure - Helsinki, 2009 |
| Key Points |
100 year old lady with leg wound resulting from a skin tear and leading to Klebsiella infection, necrotic tissue, malodorous, exposed tendon and VAS score 8/10. Suprasorb X+PHMB applied with occlusive foam. |
| Title |
The management of Pseudomonas Aeruginosa in a hard to heal arterial leg ulcer |
Download File |
| Author |
Natalie Doble |
| Publication |
Poster Presentation, TVS Conference, 2010 |
| Key Points |
The management of a lady with long-standing, chronic arterial leg ulcer heavily infected with Pseudomonas aeruginosa - a frequently isolated pathogen within chronic wounds. The wound was 100% green/yellow thick slough and the lady had a VAS score at worst of 8/10. There were high levels of odour and exudate. Previous treatment included iodine and silver sulphadiazine cream with reduced compression. |
| Title |
In vitro evaluation of polihexanide - biocompatible and effective |
Download File |
| Author |
Wiegand et al |
| Publication |
Poster Presentation, TVS Conference, 2010 |
| Key Points |
Infection is a main cause of delayed wound healing and formation of chronic wounds. PHMB has had a positive effect on wound closure in individual clinical cases and in animal models. |
| Title |
Evaluation of Suprasorb X+PHMB across a primary care organisation: A clinical & financial perspective |
Download File |
| Author |
Jackie Stephen-Haynes |
| Publication |
Poster presentation, Wounds UK Harrogate, November 2010 |
| Key Points |
The management of infection is currently high on the government agenda and has a high impact on patient morbidity and mortality. A UK PCT reviewed the management of infected wounds and concluded that availability and evidence to support the introduction of PHMB into the UK market was strong enough to evaluate Suprasorb X+PHMB, its HydroBalance and antimicrobial properties. |
| Title |
I just want to be able to swim with my grandchildren |
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| Author |
Prof. Linda Rafter |
| Publication |
Poster presentation, Wounds UK Harrogate, November 2010 |
| Key Points |
The management of a 71 year old gentleman with a long standing (18 years), non-healing venous leg ulcer in a complex wound clinic. He had a BMI of 42 and worked part time in a supermarket from Friday to Sunday Previous treatment included a hydrofibre and foam dressing under compression. |
| Title |
A clinical case study of a venous leg ulcer using Suprasorb X+PHMB |
Download File |
| Author |
Joanna Swan |
| Publication |
Poster presentation, Wounds UK Harrogate, November 2010 |
| Key Points |
The management of a 49 year old lady who is morbidly obese and has a 14 year history of venous leg ulceration to her left leg. This lady suffered with recurrent cellulitis, severe pain, multiple sensitivities and the condition of the surrounding skin due to eczema and psoriasis. It was decided to evaluate Suprasorb X+PHMB for its pain relieving and antimicrobial properties. |
| Title |
The use of topical antimicrobial therapy in burns patients: A case series |
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| Author |
Louise Baines |
| Publication |
Poster presentation, Wounds UK Harrogate, November 2010 |
| Key Points |
A case series of seven patients with a variety of burn wounds treated with Suprasorb X+PHMB over a four month period. Burns give rise to generalised immune suppression which allows micro-organisms to multiply which, if left untreated, can lead to impaired wound healing. |
| Title |
A clinical case study of a patient with a chronic hand wound using Suprasorb X+PHMB |
Download File |
| Author |
Rommel Orig |
| Publication |
Poster presentation, Wounds UK Harrogate, November 2010 |
| Key Points |
Case study of a man who had sustained a traumatic injury to his right index finger leading to amputation and a chronic non-healing wound. His past medical history included type 1 diabetes, renal failure requiring haemodialysis, micro-angiopathy with sub optimal blood supply to his right arm, neuropathy, infection and pyoderma gangrenosum requiring steroid therapy. He was wheelchair dependent and was very anxious about losing his hand. |
| Title |
Treatment of a patient with hard-to-heal leg ulcers |
Download File |
| Author |
Silva, Filipe, Cardoso |
| Publication |
Poster presentation, Wounds UK Harrogate, November 2010 |
| Key Points |
The management of a 56yr old, morbidly obese man with bilateral circumferential leg ulcers. He had an extensive past medical history and the aim of treatment was to address the bacteria within the wound, address the multiple pathologies, reduce the oedema in his legs and heal the leg ulcers, thus improving his quality of life. |
| Title |
A real life clinical practice study on the efficacy of a polyhex containing biocell.dressing in the treatment of biofilms in wounds |
Download File |
| Author |
E Lenselink and A Andriessen |
| Publication |
Poster presentation, Wounds UK Harrogate, November 2010 |
| Key Points |
In non-healing & critically colonised wounds 65-80% is associated with biofilms leading to chronic inflammation and delayed wound healing. Interim results of a clinical study using Suprasorb X+PHMB applied to 16 infected wounds containing a biofilm. Clinical sign of a biofilm was a shiny, translucent, slimy layer on a non-healing wound surface. |
| Title |
The treatment of young children with heel injuries after imnplementation of a clinical pathway using a HydroBalance dressing |
Download File |
| Author |
Alblas et al |
| Publication |
Poster presentation, Wounds UK Harrogate, November 2010 |
| Key Points |
In the Netherlands parents use their bicycles as a mode of transport for their toddlers. Accidents often happen, causing very painful heel flap injuries. A study of 20 children with these wounds, using Suprasorb X+PHMB covered with a foam dressing fixed with a retention bandage |
| Title |
An individual patient study using an antimicrobial dressing in a Community Hospital |
Download File |
| Author |
Debbie Keelor |
| Publication |
Poster presentation, Wounds UK Harrogate, November 2010 |
| Key Points |
The management of an 83 year old lady with bilateral leg ulcers following bilateral angioplasty and surgical debridement and a category 4 pressure ulcer to her heel. She has a medical history of tablet controlled diabetes. The wounds were clinically infected, highly exuding, painful and contained devitalised tissue. |
| Title |
Case study evaluating the effectiveness of a chronic hard to heal wound using Suprasorb X+PHMB |
Download File |
| Author |
Alison Johnstone |
| Publication |
Poster presentation, Wounds UK Harrogate, November 2010 |
| Key Points |
The management of a chronic hard to heal infected venous leg ulcer with Suprasorb X+PHMB in an elderly patient. Previous dressings had been unsuccessful. |
| Title |
The use of a HydroBalanced antimicrobial wound dressing in the debridement and management of an infected cannula site - a case study |
Download File |
| Author |
Susan Mason |
| Publication |
Poster Presentation, Harrogate Wounds UK 2011 |
| Key Points |
A 6 year old child, severely immunocompromised with infected, necrotic cannula site. Wary of using a silver dressing on a child SuprasorbX+PHMB was used. |
| Title |
Reduction in SSI's of children undergoing cardiac surgery |
Download File |
| Author |
Witter et al |
| Publication |
EWMA May 2011 |
| Key Points |
A 4 step plan was devised to reduce SSIs in this high risk group. The plan which included the use of Suprasorb X+PHMB achieved a significant reduction. |
| Title |
The role of the Tissue Viability Nurse in the management of diabetic foot ulceration |
Download File |
| Author |
P Scott |
| Publication |
Harrogate Wounds UK 2009 |
| Key Points |
SuprasorbX+PHMB was used on infected, painful wounds. Amputation had been mentioned but the wounds went on to healing. |
| Title |
Superabsorbent dressings under compression in Lymphoedema |
Download File |
| Author |
Justine Whitaker |
| Publication |
EWMA 2012 |
| Key Points |
Flivasorb can be used under compression bandages |
